Amoxicillin (Amoxil) price comparison 2026: cheapest pharmacy finder
Reviewed by RxGrab Pharmacy Research Team, RxGrab Editorial Team
We surveyed prices for Amoxicillin (brand name: Amoxil) across 8 major US pharmacies in April 2026. Amoxicillin is prescribed for bacterial infections including ear infections, bronchitis, and UTIs and is one of the most commonly filled prescriptions in the United States.
If you are paying out of pocket, the pharmacy you choose matters. The price difference between the cheapest and most expensive option is $34.22 per month, which adds up to $411 per year for the same pill.
Use our free Pharmacy Price Finder to compare prices for Amoxicillin and 200+ other medications instantly.
Amoxicillin prices at every major pharmacy (April 2026)
| Pharmacy | 30-day (generic) | 90-day (generic) | Program |
|---|---|---|---|
| Cost Plus Drugs | $4.87 | $12.18 | Cost + 15% + $5 |
| Costco | $4.88 | $12.20 | Member Pricing |
| Amazon Pharmacy | $7.46 | $18.65 | Prime Rx |
| Walmart | $11.47 | $28.68 | $4 Generic List |
| Kroger | $11.77 | $29.42 | Rx Savings Club |
| Rite Aid | $19.26 | $48.15 | -- |
| CVS | $21.52 | $53.80 | ExtraCare |
| Walgreens | $39.09 | $97.73 | Rx Savings |
Prices shown are estimated cash prices without insurance. With a free discount card, prices at CVS and Walgreens drop significantly. GoodRx and SingleCare both cover Amoxicillin.
Why Amoxicillin prices vary so much
Pharmacy pricing is not standardized. Each chain negotiates its own wholesale rates, sets its own markup, and runs its own discount programs. Warehouse pharmacies like Costco operate on thin margins with high volume. Retail chains like CVS and Walgreens price higher but offer convenience and widespread locations.
For Amoxicillin specifically, the generic has been available since 1998, which means multiple manufacturers compete on price. This competition keeps generic costs low at pharmacies that pass savings through to customers.
How to get Amoxicillin even cheaper
Even the best pharmacy price might not be the lowest you can pay. Here are proven ways to reduce your cost further:
- 90-day supply: Most pharmacies offer a 15-20% discount when you fill 90 days at once. Ask your doctor to write the prescription for a 90-day supply with refills.
- Discount cards: Free cards from GoodRx, SingleCare, and RxSaver can cut retail prices by 40-80%. Always ask your pharmacist to compare the discount card price against your insurance copay.
- Mail order: Amazon Pharmacy and Cost Plus Drugs ship directly to your door, often at lower prices than brick-and-mortar stores.
- Patient assistance: If your income is below 400% of the federal poverty level ($62,400 for an individual in 2026), you may qualify for free medication through manufacturer programs.
The team at Health Britannica also covers evidence-based supplement alternatives that may complement your prescription regimen.
Should you use insurance or pay cash for Amoxicillin?
This depends on your plan. If your insurance copay for generic Amoxicillin is $10-$15, that is competitive with the best cash prices. But if you have a high-deductible plan and have not met your deductible yet, you are paying full retail through your insurance, which is almost always more expensive than cash price at Costco or Walmart.
We break this decision down fully in our guide: insurance vs cash price for prescriptions.
If you are a freelancer or self-employed, you may be able to deduct prescription costs as a medical expense. The team at CeoCult covers this in detail for 1099 workers.
We track prices weekly. Get notified when Amoxicillin drops at your pharmacy.
What You Should Know About Amoxicillin
Amoxicillin is an aminopenicillin antibiotic that works by inhibiting bacterial cell wall synthesis. It is one of the most widely prescribed antibiotics in the world, used to treat ear infections, strep throat, urinary tract infections, sinus infections, and dental abscesses. The FDA first approved amoxicillin in 1972 under the brand name Amoxil, and it has been off-patent for decades. Because of its long generic history and simple manufacturing process, amoxicillin is among the cheapest prescription drugs available in the United States.
Most major pharmacies price a full course of amoxicillin (typically 14 to 21 capsules) between $4 and $8, making it one of the few antibiotics that costs less than a fast-food meal. Walmart, Kroger, and Costco all include amoxicillin on their $4 generic lists. The drug is available in multiple forms: 250mg and 500mg capsules, 125mg and 250mg chewable tablets, and oral suspension (liquid) for children. Liquid formulations cost slightly more due to flavoring and reconstitution requirements. One important pricing distinction: amoxicillin combined with clavulanate potassium, sold as Augmentin, costs significantly more, often $15 to $40 for a full course. Clavulanate extends the antibiotic's effectiveness against resistant bacteria but adds manufacturing cost.
Because amoxicillin is prescribed as a short course rather than a maintenance medication, the biggest savings strategy is simply choosing a low-cost pharmacy. Discount cards rarely improve on the already-low cash price. If your doctor prescribes amoxicillin/clavulanate and cost is a concern, ask whether plain amoxicillin would be appropriate for your specific infection. For patients with penicillin allergies, azithromycin or doxycycline serve as common alternatives, though they treat a slightly different spectrum of bacteria.
Frequently asked questions about Amoxicillin pricing
What is the cheapest pharmacy for Amoxicillin?
Cost Plus Drugs typically offers the lowest price for generic Amoxicillin at approximately $4.87 for a 30-day supply. Costco and Cost Plus Drugs are also consistently competitive. Use our Pharmacy Price Finder to compare prices for your specific dosage.
Is there a generic version of Amoxil?
Yes, generic Amoxicillin has been available since 1998 and is FDA-equivalent to Amoxil. The generic version is typically 80-90% cheaper than the brand name.
Can I use a discount card for Amoxicillin?
Yes. Free discount cards like GoodRx and SingleCare typically reduce the cash price of Amoxicillin by 40-80%. You can use a discount card even if you have insurance, and your pharmacist is required to give you the lower price if you ask.
Sources and standards behind this page
Prescription prices in the United States are set through a documented chain of list prices, pharmacy benefit contracts and federal programs, and the sources below are the primary public records of how that chain works. They are linked so a reader can check a claim here without taking this page's word for it.
- FTC report on pharmacy benefit managers documents how the middlemen between an insurer and a pharmacy set what a drug costs at the counter.
- FDA Orange Book publishes the therapeutic-equivalence ratings that decide whether a cheaper generic may be substituted for a brand.
- FDA generic drug facts sets out what "generic equivalent" means and what a manufacturer must prove before selling one.
- Drugs@FDA is the federal database of approved drug products, which establishes whether a named product exists and in what form.
- DailyMed carries the current FDA labeling for every marketed drug product, including its approved strengths and forms.
- MedlinePlus drug information is the National Library of Medicine's consumer reference for what a given medication is and how it is used.
- CMS prescription drug coverage defines the rules a Medicare drug plan formulary must follow and how it may change during a plan year.
- Medicare.gov drug coverage (Part D) states what a Part D plan is required to offer a member and how its cost stages work.
- Medicare Plan Compare is the official tool for checking what a specific plan charges for a specific drug at a specific pharmacy.
- National Library of Medicine maintains the drug and health databases the sources above draw on.
This page describes how prescription pricing and discount programs work. It is not medical advice, and what a given person pays depends on their own plan, pharmacy and prescriber.